At present, the incidence of hypertension in my country is getting higher and higher, and more and more young people find that their blood pressure has exceeded the standard through physical examination and other methods. Xiao Wang recently felt that he was easily tired and had numbness in his hands and feet. He had a physical examination at the unit a few years ago, and the results showed that his blood pressure was 160/100mmHg. It is understood that Xiao Wang’s father also suffers from high blood pressure, but his blood pressure slowly increased after the age of 50. The doctor reminded Xiao Wang that young people with elevated blood pressure can go to the endocrinology department to complete the examination to rule out secondary hypertension and see if the cause of hypertension is related to the abnormal secretion of certain hormones. Some adrenal tumors can also lead to the occurrence of hypertension. .
(Photo source: Photo Network)
Recently, Xiao Wang came to the hospital for further examination It was only later that I discovered that my high blood pressure was really related to the hormone aldosterone, and my adrenal glands indeed had a small tumor. According to Professor Zhang Huijie, director of the pituitary adrenal subspecialty of the Endocrinology Department of the hospital, different from the common primary hypertension in the elderly, the secondary hypertension caused by adrenal adenomas can be partially cured. But if not intervened early, the consequences and complications may be more serious than essential hypertension.
Many endocrine hypertensions are not detected early, and some patients even show asymptomatic clinical manifestations, and many are misdiagnosed as primary hypertension and receive simple drug treatment. But in fact, most of the causes of elevated blood pressure in patients with endocrine hypertension are related to adrenal adenomas, hyperplasia, and even pituitary diseases. If not treated in time, it may cause irreversible effects on the heart, blood vessels, kidneys, nerves, bones and other systems. damage. If hypertension is associated with limb weakness, headache, palpitations, weight gain without obvious cause and face rounding, endocrine hypertension should be vigilant. The more common ones include primary aldosteronism, Cushing’s syndrome and pheochromocytoma . If it can be diagnosed early, most patients can be cured through active and standardized treatment, and will not cause subsequent myocardial infarction, stroke and other diseases due to excessive blood pressure and excessive hormone secretion.
Therefore, Professor Zhang Huijie suggested that hypertensive patients should be screened at least once in their lifetime for the four items of hypertension (angiotensin at 4 degrees Celsius, angiotensin at 37 degrees Celsius, renin activity and aldosterone). ), determine the specific cause of hypertension, and determine whether it is primary or secondary hypertension, which is helpful for clinicians to carry out targeted treatment according to the cause. Especially young hypertensive patients should pay more attention to the four items of hypertension screening.
Professional Profile
(Image source: provided by experts)
Zhang Huijie
Deputy Director of Endocrinology and Metabolism Department of Southern Hospital, Director of Pituitary and Adrenal Subspecialty, Professor, Chief Physician, Doctor of Medicine, Doctoral Supervisor, Young Scholar of the “Changjiang Award Program” of the Ministry of Education, Outstanding Young Medical Talent in Guangdong Province, Graduated Shanghai Jiaotong University, worked as a postdoctoral researcher at Tulane University School of Public Health. Mainly engaged in the research on the pathogenesis and intervention strategies of metabolic diseases. Received the Scott Grundy Metabolism Outstanding Research Award from AHA and the American Heart Prevention Association Youth Research Award, and the research results were selected as the American AHA 2015 Outstanding Research, 2016 China Endocrine Outstanding Research Achievement, 2016 China Diabetes “Top Ten Research” and 2020 Clinical Change Practical Chinese original research “Top Ten Young Researchers”. He is a member of American Heart Association (AHA) and European Diabetes Association (EASD), a member of the Standing Committee of Guangdong Diabetes Association, a member of Guangdong Endocrinology Society, a concurrent secretary of the Youth Committee of the Diabetes Branch of the Chinese Medical Association, a member of the Obesity Group of the Diabetes Branch of the Chinese Medical Association, and a member of the Chinese Medical Association Diabetes Branch. Member of the transformation group of the Diabetes Branch of the Medical Association and director of the China Integrative Medicine Alliance. Published 26 SCI papers as the first or corresponding author in JAMA Inter Med, Diabetes Care, J Clin Invest, J Hepatol, ADV SCI, Circ Res, BMC Med and other journals. Presided over 1 national key R&D program (project leader), 3 National Natural Science Foundation of China, and a number of provincial and municipal science and technology funds, and won the third prize of the Provincial Science and Technology Progress Award, the first prize of the Municipal Science and Technology Progress Award and the city Science and Technology Innovation Outstanding Talent Award.
(author of this article/Liu Zhenghui, Li Xiaoshan, Liu Lerong, editor on duty/Xingxuan)