What is the impact of hepatitis B patients with fatty liver?

A young man in the inpatient department has hepatitis B and fatty liver.

Hepatitis B is in good condition. The virus is only 10 to the 2nd power, and he is not very old, so I have not given him anti-virus for the time being.

But fatty liver is more serious.

He is 172cm tall and weighs close to 100kg.

Liver function is characterized by elevations in ALT and GGT that are more than 2 times normal. The patient does not drink alcohol.

Typical hepatitis B combined with nonalcoholic fatty liver disease.

Many of these patients have low DNA, and abnormal liver function is closely related to fatty liver.

The treatment for such patients is mainly to control the weight first, and if the liver function is not normal after weight loss, antiviral treatment is required.

The patient cooperates well and the results are good.

Remind everyone that you must pay attention to your weight and avoid the combination of fatty liver, which will cause a double blow to the liver.

What are the symptoms of hepatitis B with fatty liver?

Most of the clinical symptoms of chronic hepatitis B combined with fatty liver are mainly clinical manifestations of fatty liver, with occasional swelling and discomfort in the liver area, and the symptoms are not typical. There are often abnormal blood lipid biochemistry through biochemical examination, and the imaging examination is consistent with the image of fatty liver. If there is obvious fatigue and loss of appetite, it should be considered whether it is an inflammatory reaction caused by hepatitis B virus.

What are the effects of hepatitis B patients with fatty liver on the patients?

If a hepatitis B patient is complicated with fatty liver, there will be dual effects of virus and hepatocyte steatosis on the liver, which will accelerate the development of liver inflammation, fibrosis and even liver cirrhosis. Increase the risk of liver cancer, even if the patient’s hepatitis B virus replication is controlled, there is still a risk of developing liver cirrhosis and liver cancer.

Hepatitis B combined with fatty liver can also reduce the effect of antiviral drugs.

After hepatocyte steatosis, a large amount of fat is deposited in hepatocytes, which will cause disturbance of liver function, destroy the normal structure of the liver, and reduce the contact area between antiviral drugs and virus-containing liver cell membranes. Causes the liver to lose the effect of antiviral drugs;

Hepatitis B combined with fatty liver can also cause antiviral drugs to fail to inhibit viral replication.

Hepatocyte steatosis can also slow down drug metabolism, reduce the sensitivity of the liver to antiviral drugs, and seriously affect the hepatic blood drug concentration and effective blood drug concentration time. Its blood concentration is lower than the average level of normal chronic hepatitis B patients, and the duration is shorter than the normal level, so that the ideal therapeutic dose cannot be achieved, and the virus replication cannot be well inhibited.

Hepatitis B combined with fatty liver can also cause a poor immune system to fight the virus. Due to the effect of fatty liver, the body’s immune system is poor and its combat effectiveness is poor.

What should a patient with hepatitis B and fatty liver do?

Therefore, for patients with hepatitis B combined with fatty liver, in addition to active and standardized antiviral treatment, they also need to change their lifestyle, adjust their diet and exercise moderately to reduce the deposition of hepatic fat deposits and improve the liver Lipid metabolism, a two-pronged approach to reducing liver inflammation, may reduce the risk of developing end-stage liver disease, such as liver failure, or the risk of developing liver cancer.

How to protect liver with hepatitis B combined with fatty liver?

1. Pay attention to food hygiene. Do not eat expired and moldy food, and eat less pickled, smoked, roasted and other foods.

2. Improve drinking water quality. Especially for people living in areas with high incidence of liver cancer, it is necessary to strengthen the removal of harmful substances in water and clean drinking water.

3. No or less alcohol. Avoid alcoholic hepatitis and damage the detoxification function of the liver.

4. Prevent excessive fat intake and strengthen physical activity. Avoid fatty liver, diabetes and other risk factors for liver cancer.

5. Increase fruit and vegetable intake. It is rich in free radical scavengers, such as apple polyphenols and vitamin C, which can effectively prevent liver cancer.

6. Have a reasonable schedule and don’t stay up late. Fatigue is the source of all diseases, and overwork can easily lead to illness. Long-term fatigue, especially staying up late, is not conducive to the rest and self-repair of the liver.

7. Be happy and not angry. Anger hurts the liver, and bad emotions can also cause great damage to the liver.

8. Rational use of medicines. Control the dose to reduce the burden on the liver and avoid the use of drugs that damage the liver.