Nowadays, most people are under heavy work pressure, and the incidence of ED problems in men is increasing. In clinical medical treatment, sildenafil is used Vardenafil and tadalafil are the first-choice drugs for male ED problems. They entered the country late, and are slightly less famous than sildenafil, but they are also the three well-known magic weapons in the ED crowd.
However, most people have only heard of these three drugs without knowing the difference .
Sildenafil, Tadalafil, Vardenafil, what’s the difference?
—Sildenafil< /span>
The peak time of sildenafil drug concentration is 1 hour, and the half-life is about 3-5h. High-fat diet can slow down sildenafil For the absorption of Nafil, the peak time of the drug concentration is extended by 30 minutes to 1 hour, so the drug taking time should be taken about 30-60 minutes before, and preferably 2 hours after meals.
The recommended dose of vardenafil is 10mg, which is characterized by a faster onset of action, about 60 minutes. Concentrations peak at peak concentrations and are also susceptible to mealtime effects.
– Vardenafil
< p data-track="8">Among the Three Musketeers favored by male ED patients, vardenafil is the fastest onset. It is understood that it only takes 10 minutes to see the effect. The effect peaks after 25 minutes and is not affected by food or alcohol.
Vardenafil has been shown by a large number of clinical studies, as a new generation of phosphodiesterase 5 inhibitor, hydrochloric acid Vardenafil has the characteristics of potency, high selectivity and good tolerance, and its advent has brought new options to the treatment of ED.
But it should be noted that vardenafil also needs to pay attention to the dose, and taking a large amount can easily cause headaches .
– Tadalafil
< p data-track="12">The pharmacokinetics of tadalafil is also variable, and the peak time of tadalafil drug concentration is about 0.5 to 12 hours, and the half-life is 17.5 hours. The effect can be maintained for 24 to 36 hours. It can be seen that the drug takes effect faster and lasts for a long time.
Some people prefer a low-dose, once-daily regimen of tadalafil, That is, tadalafil 5mg/time, once a day.
Because of the long half-life of tadalafil, which can be as long as 30-36 hours, one day You only need to take it once. In addition, a small dose of the drug will not have any impact on life, and it is more beneficial to the recovery of the patient’s condition, which has obvious advantages over other similar drugs.
What should I pay attention to when taking it?
● Use with caution
People with heart disease should use such drugs with caution, especially those with myocardial infarction, severe arrhythmia, heart failure, etc. patient.
Love sports pose a potential risk to people with heart disease, and these drugs mayAfterwards, there may be mild to moderate blood pressure changes, increased heart rate, and vascular lesions other than the heart such as vasodilation, facial flushing and other adverse reactions, which will increase the burden on the heart of patients with heart disease.
● Do not take with nitrates span>
Try to avoid taking drugs with nitrates, including nitroglycerin, isosorbide nitrate, isosorbide mononitrate, etc., otherwise It is easy to cause low blood pressure, which can be serious and even life-threatening. Generally speaking, two drugs should be taken at least 24 hours apart.
● For various functions
Diabetes with ED——Diabetes patients generally have vascular endothelial damage, so sildenafil or vardenafil is the first choice
Visual dysfunction – Tadalafil is recommended
ED with benign prostatic hyperplasia – tadalafil is recommended
To avoid back and muscle pain – Sildenafil or vardenafil is recommended.
Summary:
< p data-track="27">Sildenafil, tadalafil, and vardenafil are all commonly used drugs in the treatment of male ED, and each drug has its own characteristics in the treatment of ED Efficacy characteristics, before male friends choose drugs, it is best to choose according to their own conditions and the doctor’s advice, do not choose blindly, so as to avoid adverse situations.
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