Reminder: Smoking and drugs “combine”? Doctors are worried about patients smoking after taking these 12 drugs

Smoking is harmful to health. It not only damages the lungs, mouth and esophagus, blood vessels, etc., but also affects the efficacy of drugs, making the drugs ineffective. The study found that smoking within 30 minutes before and after taking the drug can reduce the drug content in the blood, and also delay the emptying of the stomach contents and delay the absorption of the drug. In particular, smoking should be avoided when taking the following drugs.

Which medicines should I avoid smoking?

1. Sedative and hypnotic drugs

The common sedative and hypnotic drugs in life include diazepam and alprazolam . Cigarette smoke contains too many harmful substances, only a few of which are polycyclic aromatic hydrocarbons, which promote the rapid metabolism of drug components in the blood. In addition, cigarettes also contain nicotine. When nicotine reaches a certain level, it will stimulate the central nervous system, excite the central nervous system, and weaken or offset the sedative and hypnotic effects of drugs.

2. Diuretics

Cigarettes contain nicotine, which can reduce the concentration of furosemide in the blood. Reduce the diuretic effect.

3. Antidepressants

The widely used antidepressants include chlorpromazine and amitriptyline, etc. Smoking can reduce the concentration of these drugs in the blood, making antidepressants less effective.

4. Antipyretic analgesics

Smoking can speed up the metabolism of antipyretic and analgesic in the body, reduce the efficacy of the drug, and make the antipyretic and analgesic ineffective. In addition, metabolites are not easily excreted, which makes drug components easy to accumulate in the body, resulting in drug poisoning.

5. Antiasthmatic drugs

A common antiasthmatic drug is aminophylline, which is used to treat bronchial asthma. Smoking can reduce the efficacy of such drugs, the drugs are easily destroyed and excreted rapidly in the body, thereby weakening the anti-asthmatic effect and shortening the maintenance time of the drugs.

6. Contraceptive pills

Studies have shown that if a woman is a heavy smoker, the use of oral contraceptives Avoid pregnancy, then the risk of myocardial infarction is several times higher.

7, hypoglycemic drugs

< p>Smoking can stimulate the release of catecholamines. Catecholamines are not good substances. They can affect peripheral vasoconstriction and hinder the absorption of insulin. Smoking also stimulates endogenous substances, which antagonize insulin, thereby reducing the efficacy of insulin. Whether it is oral hypoglycemic drugs or insulin injections, you should not smoke, so as not to reduce the efficacy of the drugs and make it difficult to control blood sugar.

8. Aerosols

Due to prolonged smoking, there is a layer of smoke tar in the trachea, which affects the absorption of gas by the organs. nebulizers, thereby reducing the efficacy of the drug.

9. Vitamins

Vitamin C is an antioxidant that can scavenge free radicals, improve immunity, and prevent nitrous acid The salts are converted into nitrosamines, which prevent blood lipid levels from getting too high. However, concomitant smoking can reduce the concentration of the drug in the blood.

10, antianginal drugs

< p>Patients with angina pectoris often smoke. After taking some anti-angina pectoris drugs, the concentration of drugs in the blood decreases significantly, and it also promotes drug excretion.

11. Antacids

Patients with gastric or duodenal ulcers need to take antacids. Smoking can promote vasoconstriction, delay gastric emptying, reduce the rate of drug absorption, weaken the efficacy of drugs, and affect the healing of ulcers.

12. Anticoagulants

Smoking before and after taking anticoagulants significantly shortens the plasma half-life of heparin and reduces the The concentration of the drug in the blood will ultimately affect the efficacy of the drug.

Message from the doctor

All in all, do not smoke within 30 minutes before and after taking the above medicines, the most It is better to quit smoking, so as not to affect the efficacy of cigarettes. There is no harm in smoking, it is imperative to quit smoking, establish the determination to quit smoking, throw away everything related to cigarettes, try not to contact old smokers; adopt the principle of step by step to quit smoking, prolong the interval between two cigarettes, and gradually reduce the daily cigarette smoke. The amount of cigarettes you smoke until you quit smoking completely.

Family doctor online feature, unauthorized reprint