Lipoprotein a, there is no treatment, should I check it? The doctor said: It’s time to check! Has 2 clinical effects

Uncle Wang usually likes to read medical science, and gradually he can understand the clinical significance of some laboratory indicators. No, when Uncle Wang saw me, he asked: “Doctor Zhang, since there is no cure for lipoprotein a, what’s the use of checking it? It’s better not to check it!”

I explained to Dr. Zhang the clinical significance of checking lipoprotein a in detail. After listening to my answer, he said: “This test index really needs to be checked, this time I understand, It seems that everyone really needs to check lipoprotein a once.”

Does lipoprotein a have to be checked?

Today, I will tell you what I explained to Dr. Zhang and Uncle Wang. You can also listen to why each of us should check lipoprotein a once in our life.

First of all, the blood lipid index of lipoprotein a is high, and there is indeed no effective treatment at this stage. Fans and friends who follow Dr. Zhang Zhiying all know that lipoprotein a, a blood lipid indicator, is only affected by genes and heredity, and the external environment, diet and drugs cannot affect its increase or decrease. Therefore, although people have seen that it is also a “bad blood lipid” that forms atherosclerotic diseases, at this stage, there is no effective way for humans to take it. So many people mistakenly believe that it does not make much sense to check this blood lipid index. In fact, this kind of understanding is very wrong, because it is clear that this indicator has two practical effects in clinical practice, and can specifically guide clinicians to adjust treatment plans for patients. Let me tell you about the two clinical effects of lipoprotein a:

Blood lipid test sheet

1. Lipoprotein a can guide the treatment of blood lipids

After checking lipoprotein a, for those with elevated, especially markedly elevated lipoprotein a, a comprehensive assessment of their cardiovascular disease risk stratification may require lower LDL. For example, if a patient’s low-density lipoprotein should be lowered to 2.6 mmol/l before checking lipoprotein a, then after checking lipoprotein a, if it is found that lipoprotein a is abnormally elevated, it may be that low-density lipoprotein It is about to be reduced to 1.8mmol/l. This is the first meaning of lipoprotein a to guide clinical practice.

Low density lipoprotein needs to be more up to standard

2. Lipoprotein a can guide the use of aspirin

In clinical practice, there are some patients, although they have not been diagnosed with cardiovascular and cerebrovascular diseases, but their cardiovascular disease risk stratification is high or very high risk. The “Guidelines for Primary Prevention of Cardiovascular Diseases in China” released in 2020 pointed out that for these patients, lipoprotein a can be further checked, and lipoprotein a can be defined as a risk-enhancing factor. If this risk-enhancing factor is increased, especially if it is abnormally increased, and other cardiovascular disease risk factors of the patient are comprehensively considered, the patient can consider taking aspirin or not under the guidance of a professional doctor. Note that the use of aspirin must be carried out under the guidance of a professional doctor.

As a reference factor for taking aspirin or not

After reading the above two points, it is estimated that no one will say that it is useless to check lipoprotein a. In fact, everyone should check the indicator of lipoprotein a in their lifetime. Check, but check once in a lifetime to know whether your index is high or not, it is still very necessary.

The above is Dr. Zhang’s interpretation of this issue. I hope it can help more people and let more people know that lipoprotein a is indeed a blood lipid indicator that needs our special attention. attract more people’s attention.

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