How was vitamin D discovered?
In 1914, American researchers Elmer McCollum and Marguerite Davis discovered a Substance, later called “vitamin A”.
From 1919 to 1920, the British doctor Edward Mellanb found that rickets occurred in dogs fed with oatmeal without exception, and feeding fat or cod liver oil could prevent it from happening. By 1922, Elmer McCollum discovered that if oxygen was introduced into cod liver oil to destroy the vitamin A in it, rickets in dogs could still be cured. Therefore, he believed that it was not vitamin A but another substance that could cure rickets in cod liver oil. Three vitamins were discovered, so this fourth vitamin was called “vitamin D”.
It turns out that vitamins ABCDE also come in the order of “birth”…
Vitamin D goes beyond calcium absorption
Vitamin D3 is known to promote calcium absorption, and now with research The in-depth discovery of it actually has many roles, including roles in cardiometabolism and immunity, as well as in regulating human reproduction. Vitamin D3 insufficiency (VDD) is still very common around the world, because foods with naturally high vitamin D content are limited, and obesity, indoor sedentary lifestyle, use of sunscreen, etc. can lead to a rise in VDD, most medical institutions believe that When the vitamin D3 level of pregnant women is <25nmol/L, it is insufficient, and the risk of pregnancy increases.
How does vitamin D affect women?
Medical research suggests vitamin D3 deficiency in pregnant women is more affected , For the mother itself, the risk of gestational diabetes, postpartum depression, and recurrent miscarriage is increased. Greater impact on the fetus, associated with intrauterine growth restriction, decreased bone mineral content in infants and children, muscle weakness and rickets, autoimmune disease, cardiovascular disease, diabetes, neurological disease, and cancer in adulthood The probability of occurrence will also increase.
Vitamin D and recurrent miscarriage
recurrent Vitamin D deficiency is common among miscarried women. The data show that the vitamin D level of pregnant women with recurrent miscarriage, about 70% of pregnant women with recurrent miscarriage, has a vitamin D level of 15ng/ml, which is a certain distance from the normal value of 30ng/ml. This data surprised us a bit, the vitamin D of recurrent miscarriage is really lacking! The possible reason for this is that women with recurrent pregnancy failure (RPL) and recurrent implantation failure (RIF) have auto- and cellular immune abnormalities, and vitamin D plays a major role in regulating auto- and cellular immune abnormalities, and is responsible for various immune effectors ( including T, B and NK cells) have immunomodulatory functions.
Researchers from the National Institutes of Health found that women who were planning to become pregnant after a miscarriage had adequate vitamin D intake compared to women who were not getting enough vitamin D. High levels of vitamin D may increase the chance of pregnancy and live birth.
Vitamin D and polycystic ovary syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is the leading cause of female infertility, the most common endocrine disorder in 9-18% of women. Compared with PCOS patients without metabolic syndrome, women with both metabolic syndrome and PCOS had lower vitamin D levels (45.4 and 27.4 nmol/L). There are also data showing that vitamin D supplementation increases endometrial thickness, increases menstrual flow, and promotes follicular maturation.
Some studies first suggested that vitamin D deficiency might be a risk factor for PCOS. The study found that vitamin D deficiency (25-OH-VD < 25 nmol/L) was significantly different in 44% of PCOS patients and 27% of healthy women. The study concluded that vitamin D deficiency may be a risk factor for PCOS. The study found that low serum vitamin D levels did significantly increase the risk of PCOS.
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Source: Internet
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