Evening News | Study Reveals No ‘Healthy Obesity’

1, Modena applies for emergency use authorization of bivalent COVID-19 vaccine for people aged 6 to 17 in the United States

Modena recently posted on social platforms that the company has applied to the US FDA for emergency use authorization of the bivalent new crown vaccine for people aged 6 to 17. Applications for children aged 6 months to under 6 years are expected to be completed later this year. The bivalent new crown vaccine that Moderna is applying for approval this time targets the original strain and the Omicron BA.4 and BA.5 variant strains. (Prospective Network)

2.Study reveals no ‘healthy obesity’

Recently, a reporter from Science and Technology Daily learned from the First Affiliated Hospital of Chongqing Medical University that the team of Professor Li Qifu from the Department of Endocrinology of the hospital explored the causal relationship between fat content and death risk based on genetic analysis. There are “healthy lean” and “unhealthy lean” for people with low fat content; but there is no “healthy obesity” for people with too much fat. Relevant research results were published in the international journal “Metabolism”.

This study, based on a large UK Biobank cohort, used two different methods to assess the relationship between total body fat content and risk of death. The researchers first combined genome-wide association studies, polygenic risk scores and Mendelian randomization methods to analyze the relationship between fat content and risk of death. The results showed that there was a linear causal relationship between fat content and all-cause mortality. 1kg/m2, the risk of death increased by 8%. The researchers then used bioelectrical impedance to measure the fat content and analyzed its relationship with the risk of death. The results showed that the fat content and the risk of death were non-linear, that is, too little or too much fat increased the risk of death. (Science and Technology Daily)

3. Shijiazhuang Police: Failure to report mixed positive samples caused the spread of the epidemic, and a nucleic acid testing institution was placed on file for investigation

Shijiazhuang Municipal Public Security Bureau reported on September 24 that in view of the recent continuous outbreak of epidemics in Yuhua District and the source is unknown, Shijiazhuang Municipal Health Commission, Municipal Public Security Bureau and other departments have dispatched relevant professional experts to conduct nucleic acid analysis in the city. Inspection agencies conduct inspections. During the inspection, it was found that the positive sample of a 20:1 mixed tube of nucleic acid detected by the “Hebei Hehe Medical Laboratory Laboratory” in Zhengding County on September 14, 2022 in the Sunshine 361 Community in Yuhua District was not reported, resulting in the relevant personnel not being received in time. Control, resulting in community transmission on September 21. The laboratory is suspected of illegal crimes, and the police have opened a case for investigation. (Interface News)

4.The latest situation of the novel coronavirus pneumonia as of 24:00 on September 23

From 0 to 24:00 on September 23, 31 provinces (autonomous regions and municipalities) and the Xinjiang Production and Construction Corps reported 188 new confirmed cases. Among them, 59 were imported cases (15 in Shanghai, 15 in Guangdong, 5 in Fujian, 4 in Inner Mongolia, 4 in Yunnan, 3 in Tianjin, 3 in Liaoning, 2 in Beijing, 2 in Jiangsu, 2 in Shaanxi, and 1 in Heilongjiang). , 1 case in Hubei, 1 case in Chongqing, 1 case in Sichuan), including 6 cases converted from asymptomatic infections to confirmed cases (3 cases in Guangdong, 1 case in Tianjin, 1 case in Liaoning, 1 case in Fujian); 129 local cases (51 in Sichuan, 32 in Guizhou, 21 in Heilongjiang, 11 in Tibet, 5 in Guangdong, 3 in Tianjin, 3 in Yunnan, 1 in Hunan, 1 in Hainan, and 1 in Xinjiang), including 24 cases of asymptomatic infection The patients were converted into confirmed cases (9 in Sichuan, 6 in Heilongjiang, 4 in Guizhou, 3 in Guangdong, 1 in Yunnan, and 1 in Xinjiang). No new deaths were reported. No new suspected cases were reported.