In the human body, the normal adult has two kidneys, located behind the sides of the waist. It is responsible for filtering impurities in the blood, maintaining the balance of body fluids and electrolytes, and finally producing urine, which is excreted through the urethra, and also has the function of endocrine to regulate blood pressure.
01
The function of the kidneys< /strong>
1. Urine is generated and metabolites are excreted. The body produces various wastes in the process of metabolism, most of which pass through glomerular hemofiltration However, the secretion of renal tubules is excreted with urine, that is, the kidneys are the organs of detoxification.
Second, to maintain fluid balance and acid-base balance in the body, the kidneys filter through the glomerulus, reabsorption and secretion function of the renal tubules, and excretion The excess water in the body regulates the acid-base balance and maintains the stability of the internal environment.
Third, endocrine function. The kidneys secrete renin, prostaglandins, and kinin to regulate blood pressure through the renin-angiotensin-aldosterone system and the kinin-bradykinin-prostaglandin system.
Fourth, in addition, the kidney can also stimulate erythropoietin and stimulate bone marrow hematopoiesis. At the same time, the kidney is also a site for the degradation of many endocrine hormones, such as insulin and gastrointestinal hormones.
It is enough to see that the importance of the kidney is self-evident, but in recent years, due to people’s poor living and work and rest habits, the kidney is very injured, and people with kidney disease Also increasing year by year.
Related data show that about 100 million people in China have nephritis, and the incidence of chronic kidney disease in Chinese adults is 10.8%. rate is still high. Among them, chronic kidney disease is known as the “silent killer” because of its low awareness rate, high morbidity and high mortality rate, and people’s vigilance should be aroused.
02
Can kidney disease progress to kidney failure ?
Patients with nephrotic syndrome may not all develop renal failure, and some patients may get better proteinuria after treatment. Control, the patient’s renal function will remain at a normal level, but some patients will develop renal failure.
Generally speaking, it takes more than ten years for nephrotic syndrome to develop to renal failure, and it may take decades for the development of nephrotic syndrome. To renal failure, relatively speaking, the disease progresses relatively slowly, and the rate of development to renal failure is also relatively slow. But if a patient with nephrotic syndrome develops complications, such as acute renal failure, the progression to renal failure is relatively faster.
03
These 4 indicators will remind you , one can meet the standard
[Urine protein more than 1g for 3 months] span>
If the physical examination has just detected urine protein 2+, the quantitative amount is less than 1g, and there are no symptoms, the impact on renal function is relatively small, and the basic can be treated conservatively. However, if the urine protein is more than 1g for about three months, then drugs are needed to control it., This stage requires adjuvant drugs for anticoagulation, lipid lowering, diuresis and other treatments.
[Blood pressure level above 130/80 for 3 months]
. For patients with kidney disease, blood pressure is also a more sensitive indicator. Elevated blood pressure will induce a series of diseases. If it persists for more than 3 months at 130/80, it may affect kidney function. , it is time to be more vigilant.
[creatinine level over 130umol/L]
This is also a sensitive indicator in the middle and late stages of renal disease. If the creatinine level has been rising and the creatinine level exceeds 130umol/L, it is necessary to consider whether it is an acute factor affecting renal function, but there is still a reversal at this stage. room, as long as actively cooperate with the doctor’s treatment.
[Glomerular Filtration Rate]
Generally, a glomerular filtration rate lower than 90 indicates that the renal function begins to decline. In the stage of 60-90, it is a key node of renal disease, and the deterioration is slow and there is room for recovery.
Therefore, the doctor hereby reminds: kidney disease may develop into kidney failure, but it depends on the patient’s own situation, not absolute. If the above 4 indicators only account for one, the renal function damage is not serious, and there may be a chance of reversal.