Antiplatelet drug linked to heat-related heart disease

This article is reprinted from: Guangming.com

According to a study published in “Nature-Cardiovascular Research” on August 1, the use of antiplatelet drugs and beta-blockers may Increased risk of non-fatal heat-related heart disease in patients. But the researchers say further studies are needed to confirm this effect.

It has been previously shown that both exposure to cold and heat can induce heart disease. Previous epidemiological studies have shown that with a global warming of 2°C to 3°C, the burden of heart disease associated with heat will increase.

In this study, Kai Chen and colleagues from the Yale School of Public Health in New Haven, Connecticut, USA, analyzed 2,494 people in Augsburg, Germany, from May to September each year from 2001 to 2014. data on patients who experienced a heart attack in the Fort area and compared the patients’ clinical information, daily weather information, and medication intake.

Among the reported drugs, researchers observed a higher risk of non-fatal heat-related heart disease among patients taking antiplatelet drugs and beta-blockers, two conventional cardiovascular drugs This was more pronounced in patients who did not use such drugs.

The researchers also found that this effect was higher in younger patients (25-59 years) than in older patients (60-74 years)—a population with lower rates of prior coronary heart disease .

The nature of the data does not rule out the possibility, the researchers suggest, that the higher risk was due to the fact that patients on antiplatelet drugs and beta-blockers were more ill, with severe disease It is more prone to high temperature-related heart disease. To answer this question, further studies enrolling more patients are needed.

Chen Kai and collaborators believe the findings could help develop targeted strategies to reduce the burden of cardiovascular disease associated with rising temperatures.