In recent months, major cities such as Shanghai, Guangdong and Beijing have been ravaged by the new coronavirus, and asymptomatic infections have appeared almost every day. Among them, the number of new deaths in Shanghai has increased, causing people to panic. Once infected with the new coronavirus, the lungs will bear the brunt, and it will also damage the liver, kidneys and other organs. Let’s take a look at how the new coronavirus damages the liver.
How does the new coronavirus damage the liver?
1. Immune damage
Studies have shown that there is a close relationship between COVID-19 and liver damage. COVID-19 can induce liver damage and affect immune mechanisms. After being infected with the new coronavirus, the virus damages the body through two mechanisms. One is that the new coronavirus directly acts on the cells. The new coronavirus itself does not reproduce, but only replicates in the cells, so that the cells lose their original functions, resulting in cell damage; One is that after the new coronavirus invades the cell, it leaves a unique mark in the cell.
After the body’s immune system recognizes the mark, it is clear that the cell has been infected by the virus, so it begins to clear the cell. When the immune system clears the new coronavirus, it will inevitably damage liver cells, which will lead to liver damage and, in severe cases, can induce liver failure. The risk of liver injury in patients with mild new coronary pneumonia is low, and the risk of liver injury in severe patients is high.
2. Drug factor p>
Fever is a common symptom of new coronary pneumonia. Most patients will take antipyretics, which contain acetaminophen, which can damage the liver. In addition, some patients with new coronary pneumonia will take oseltamivir, lopinavir or hydroxychloroquine, etc., such drugs can also damage liver function. Especially when the medication is more and more complicated, patients with new coronary pneumonia are prone to liver damage, so they should be highly vigilant.
3. Systemic inflammatory response
The early symptoms of new coronary pneumonia are not very obvious, but In as little as a week or so, the disease progresses to the point of multiple organ failure, including the liver. This problem may occur because immune cells release too many inflammatory cytokines, causing systemic inflammatory response syndrome, or causing acute respiratory distress syndrome.
4. Organ ischemia-hypoxia-reperfusion injury
After respiratory failure in patients with new coronary pneumonia, the oxygen content in the blood is reduced, which makes the whole body hypoxia, and the brain is most sensitive to hypoxia. Hypoxia will affect all tissues and organs in the body, and the liver is no exception. After right heart failure in patients with new coronary pneumonia, blood cannot return to the heart normally, causing a large amount of blood to accumulate in the body, and some blood accumulates in the liver, which can easily induce congestion in the liver and cause liver damage.
Message from the doctor
Since it is known that the new coronavirus can damage liver function, it should be actively prevented. Especially those with basic liver disease, try not to go out unless necessary, wear disposable medical masks or N95 masks when going out, and keep a distance of more than one meter from others. Avoid public transportation by walking, cycling or driving.
Regularly open windows in the living room for ventilation to ensure indoor air circulation. Pay attention to personal hygiene, wash hands frequently with soap and running water; avoid rubbing eyes, mouth and nose with dirty hands. Reduce the number of times you eat out, whether you eat at home or when you eat out; cook food thoroughly, especially eggs and meat; separate knives and cutting boards for raw and cooked food to avoid crossovers Infect.
Family doctor online feature, unauthorized reprint